منابع مشابه
Hematopoiesis: Wandering progenitor cells
The generation of mice that are chimeric for expression of alpha 4 integrin has revealed a critical role for this adhesion molecule, specifically in postnatal lymphopoiesis.
متن کاملProgenitor cells in canine cyclic hematopoiesis.
Granulocytic (colony-forming units in culture, or CFU-c) and erythrocytic (erythropoietin-responsive cells, or ERC) progenitor cells in canine cyclic hematopoiesis (CH) have been shown to fluctuate over the cycle and in the same phases as one another. The ERC cycle is preceded by 3 or 4 days by a rise in serum erythroid-stimulating activity and is followed by a reticulocytosis. During the cycle...
متن کاملAdult somatic progenitor cells and hematopoiesis in oysters.
Long-lived animals show a non-observable age-related decline in immune defense, which is provided by blood cells that derive from self-renewing stem cells. The oldest living animals are bivalves. Yet, the origin of hemocytes, the cells involved in innate immunity, is unknown in bivalves and current knowledge about mollusk adult somatic stem cells is scarce. Here we identify a population of adul...
متن کاملTC1(C8orf4) Regulates Hematopoietic Stem/Progenitor Cells and Hematopoiesis
Hematopoiesis is a complex process requiring multiple regulators for hematopoietic stem/progenitor cells (HSPC) and differentiation to multi-lineage blood cells. TC1(C8orf4) is implicated in cancers, hematological malignancies and inflammatory activation. Here, we report that Tc1 regulates hematopoiesis in mice. Myeloid and lymphoid cells are increased markedly in peripheral blood of Tc1-delete...
متن کاملHEMATOPOIESIS AND STEM CELLS cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis
The establishment of the HSC pool in vertebrates depends not only on the formation and the propagation of these stem cells but also on their proper trafficking among the defined hematopoietic organs. However, the physiologic mechanisms that regulate HSC mobilization remain elusive. Through analysis of the zebrafish cmyb mutant cmybhkz3, we show that the suppression of cMyb function abrogates la...
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ژورنال
عنوان ژورنال: Current Biology
سال: 1996
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)70705-7